Preparation and Characterization of Solid Complexes of Naphtoquinone and Hydroxypropyl-b-Cyclodextrin

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Preparation and Characterization of Solid Complexes of Naphtoquinone and Hydroxypropyl-β-Cyclodextrin

The formation of an inclusion compound between a naphthoquinone derivative (I) and HP-ß-CD was studied in solid state by X-ray diffractometry, DSC, and IR. Introduction The formation of inclusion complexes with cyclodextrins constitutes a widely used strategy to increase the aqueous solubility and to decrease the countereffects of many drugs. Isoxazolylnaphthoquinones belong to a family of comp...

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Development and Characterization of Paracetamol Complexes with Hydroxypropyl-?-Cyclodextrin

Paracetamol is a sparingly soluble bitter tasting drug. It is widely used as an analgesic and antipyretic. Complexation of drug with different cyclodextrins (?, ? and HP-?-CD) was attempted to improve solubility of Paracetamol. During the drug excipient interaction studies, ?, ? cyclodextrins elicited analytical interference and showed considerable absorbance at ?max (243.5 nm) of Paracetamol w...

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Development and Characterization of Paracetamol Complexes with Hydroxypropyl-?-Cyclodextrin

Paracetamol is a sparingly soluble bitter tasting drug. It is widely used as an analgesic and antipyretic. Complexation of drug with different cyclodextrins (?, ? and HP-?-CD) was attempted to improve solubility of Paracetamol. During the drug excipient interaction studies, ?, ? cyclodextrins elicited analytical interference and showed considerable absorbance at ?max (243.5 nm) of Paracetamol w...

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development and characterization of paracetamol complexes with hydroxypropyl-?-cyclodextrin

paracetamol is a sparingly soluble bitter tasting drug. it is widely used as an analgesic and antipyretic. complexation of drug with different cyclodextrins (?, ? and hp-?-cd) was attempted to improve solubility of paracetamol. during the drug excipient interaction studies, ?, ? cyclodextrins elicited analytical interference and showed considerable absorbance at ?max (243.5 nm) of paracetamol w...

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synthesis and characterization of potentially biological active cyclometallated organoplatinum(ii) complexes

this work is presented in five parts. in the first part preparation of the starting complex [pt(c^n)cl(dmso)], 1, in which c^n = n(1),c(2?)-chelated, deprotonated 2-phenylpyridine, and dmso = dimethylsulfoxide, and its reaction with 1 equiv of the biphosphine ligands bis(diphenylphosphino)amine, dppa, or bis(diphenylphosphino)methane, dppm, to give the complex [pt(c^n)cl(dppa)], 2, or [pt(c^n)c...

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ژورنال

عنوان ژورنال: Molecules

سال: 2000

ISSN: 1420-3049

DOI: 10.3390/50300342